In my first degree I used a laptop for my notes. I even struggled through calculus and higher level physics and all the keyboard-unfriendly symbols. I had Microsoft Onenote, which saved automatically, and had a much looser format. You could click anywhere and begin typing and it would be a separate, manipulable block of text. It even had an easy draw feature, plus a search feature so you could find whatever you wanted without having to remember exactly where you made. Oh, and an awesome folder/notebook structure that let you easily get to any of your notes.
The one drawback was easy distraction while in boring, easy, uninteresting classes. I became a bejeweled expert.
I now have Onenote again and am going to start taking notes with it in my Ed classes. While none of them are uninteresting, the potential for distraction still remains. Let's see if I've grown out of it, or if it's a constant for me.